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Tobacco tax increases have been also been a significant cause of smuggling and black market cigarette products
Cytisine has been available since 1974 (initially without, later with reimbursement), and nicotine replacement therapy (NRT) from the beginning of the 1980s 28,29
Significantly decreased live birth rates were also reported among 166 couples seeking pregnancy through ART.73 Based on only one study, men who smoked for more than 5 years presented a higher risk of multiple births during IVF or GIFT.74 The number of oocytes retrieved from patients decreased by 46% in case the respective partners used to smoke
